Methallylescaline
One of the less well-known synthetic psychedelics in the phenethylamine chemical class is MAL (methyllescaline). It is allylescaline’s 4-methyl analogue. Alexander Shulgin was the first to synthesize methallylescaline, which he detailed in his book PiHKAL: A Chemical Love Story. According to anecdotal reports, methallylescaline and mescaline are the most similar.
Methallylescaline most likely functions as a partial agonist of 5-HT2A. Methallylescaline’s effectiveness at 5-HT2A receptors is thought to be the source of the psychedelic effects. Nevertheless, it is still unclear how these interactions contribute to the psychedelic experience.
This research chemical is exclusively intended for use in scientific, educational, and in vitro laboratory research. Not for use by veterinarians or humans.
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Chemical Name: 4-methylallyloxy-3,5-dimethoxyphenethylamine
Form: Fumarate salt
Molecular Formula: C14H21NO3
Molar Mass: 251.326 g/mol
IUPAC: 2-{3,5-Dimethoxy-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}ethan-1-amine
CAS Number: 207740-41-8
Methallylescaline, or 4-methallyloxy-3,5-dimethoxyphenethylamine, is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. Methallylescaline contains two methoxy functional groups (CH3O-) which are attached to carbons R3 and R5 of the phenyl ring.
Methallylescaline is substituted at R4 with a methallyloxy chain. This three carbon chain consists of a R2 methyl substituted allyl group with a double bond on the terminal carbon. This chain is connected to the phenyl ring at R4 through an ether (oxygen) bridge.
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